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    THE VANCOMYCIN WON'T CALCULATE ITSELF

      YOUR PATIENT CALCULATION METHOD RESULTS
      CHARACTERISTICS
      required for all calculations
      Sex
      Ageyears
      Heightcm
      Weightkg
      SCrmg/dL
      Trough Target -
      CALCULATIONS
      Override CrClml/min
      Override VdL

      CrClml/min
      VdL
      BMIkg/m2
      BSAm2
      IBWkg
      TEST DOS EQS
      INITIAL EMPIRIC
      For when reliable levels are not available
      Recalculate and redose if clearance changes
      Weight only LD Calculated LD
      Loading Dose Suggestionmg
      Loading Dose Peakmcg/ml
      STEADY STATE TROUGH
      Greatly improved by calculated Vd
      Unstable in the first few days of therapy
      Previous
      mghr
      Trough Resultmcg/ml
      Dose to Trough Timehr
      Time Adjusted Troughmcg/ml
      PEAK - TROUGH
      Peak >30 min post infusion, longer in poor clearance
      Draw trough >1 half-life after peak
      Peak Levelmcg/ml
      Trough Levelmcg/ml
      Time Between Levelshr
      SINGLE DOSE TO LEVEL
      For an educated guess when not at steady state
      Previous level and initial time passed are optional
      Previous Levelmcg/ml
      Time Passedhr

      Single Dosemg
      Time Passedhr
      New Random Levelmcg/ml
      MANUAL CLEARANCE
      For guess and check with various clearances
      Hourly Vanco Clearance%
      CrCl Would Beml/min
      Select dosing method
      Describe your patient
      Click to evaluate
      Use precise timing

      CALCULATE TIME PASSED
      assists with most dosing methods
      Earlier Time :
      Later Time :
      Difference Between Timeshr
      Click a regimen for PK predictions or
      Manually enter any regimen
      mg qh

      STANDARD DOSING
      peak
      trough
      Dosing Interval
      Dose
      in mg
      q8h q12h q24h
      500
      750
      1000
      1250
      1500
      1750
      2000

      BEST REGIMENS
      regimen Trough in range Minimal peak t1/2 /
      frequency
      Good AUC/MIC
      PHARMACOKINETICS
      Hourly Vanco Clearance%
      Half-Lifehr
      Level Drops to Target In...hr
      Limit empiric dose No limit
      Troughs/Peaks AUC/MIC Both
      SETTINGS PK TOOLS
      PK ASSUMPTIONS
      Override Infusion Timehr
      Current Dose Infusion TImehr
      Max Safe Peakmcg/ml
      S aureus MICmg/L
      Max Safe AUC24/MIC
      Min Effective AUC24/MIC
      AUC Method
      TRENDING SERUM CREATININE
      Estimates clearance when SCr not at steady state
      Only useful for dosing with empiric method
      Earlier SCrmg/dl
      Later SCrmg/dl
      Time Between SCr Drawshr
      SCr Half-Lifehr
      Renal Clearanceml/min
      Apply Renal Clearance
      VD CALCULATOR
      From peak after first dose
      Greatly improves estimates for remainder of therapy
      First Dosemg
      Peak Levelmcg/ml
      Calculated VdL
      Apply Calculated Vd
      LEVELS AND KNOWN CLEARANCE
      Guess and check tool for dosing
      Use only needed fields
      Hourly Vanco Clearance%
      Last Known Levelmcg/ml
      Time Passedhr
      Level Before Dosemcg/ml
      Single Dosemg
      Level after Dosemcg/ml
      Level Drops to Target In...hr
      BONUS TPN CALCULATORS
      TPN Variables...
      Custom Lipid Calorieskcal/g
      Custom Fluid NeedsmL/kg
      Serum Calciummg/dL
      Serum Albuming/dL
      Corrected Calciummg/dL
      Dextroseg
      Amino Acidsg
      Lipidsg
      Total KcalKcal
      Percent Lipids%
      Estimated Fluid NeedsmL
      DRIP RATE CONVERTER
      align fields to left rather than right, .entry span in orignal uses position: absolute; left: 130px;
      also need to make field heights the same.
      Current Rate /
      Desired Rate /
      Patient Weightkg
      To calculate concentration may use:
      Mass/Volume %
      or:
      Ingredient Mass
      Diluent Volume
      or just enter manually:
      Concentration

      RESULT

      WARFARIN
      Days Ago 7654321
      INR
      Dose
      Remain
      Sum Warfarin Week Beforemg
      Mean Warfarin Dosemg
      • use warfarin half life and factor halflives to tell effect, then a variable based on patient response so far to predict future.
      • ke of warfarin if t1/2 is 40 = 0.017325
      • 24 1 3299.6 / 5000 = .65992
        48 2 2177.5 / 5000 = .4355
        72 3 1437 / 5000 = .2874
        96 4 948.3 / 5000 = .18966
        120 5 625.8 / 5000 = .12516
        144 6 413 / 5000 = .0826
        168 7 272.5 / 5000 = .0545
        <5% left after 7 days
      PAIN
      Nothing to see here
      CONTROL PANEL
      COLOR CENTER
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